Your Complete Guide to Cagrilintide
Cagrilintide: Your Weight Loss GLP-1 Booster
Cagrilintide is a long-acting amylin analog that works on amylin receptors in the brain, complementing GLP-1 therapy. Amylin is a naturally occurring hormone that helps regulate appetite and metabolism.
Mechanism of Action:
- Binds to amylin receptors - reducing appetite and increasing feelings of fullness
- Slows gastric emptying - keeping you satiated longer after meals
- Supports blood sugar regulation by controlling post-meal glucose spikes
- When paired with GLP-1, Cagrilintide synergizes to enhance satiety, control cravings, and improve metabolic efficiency.
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Dosing Protocol
Suggested once-weekly injection approach through your abdomen, thigh, or back of arms.
- Weekly Dose: Start at 0.4 mg–0.6 mg; increase in phases
- Frequency: Inject once per week subcutaneously
- Cycle Length: 8–16 weeks, extend as needed for ongoing management
- Maximum Dose: Up to ~4.5 mg weekly in advanced protocols

Reconstitution Instructions
- Reconstitute your Cagrilintide with 1.5mL of bacteriostatic water as the standard dilution.
- Gently swirl (do not shake) until fully dissolved.
- Rest for at least 30 minutes in the fridge before first use. (2–8 °C). DO NOT FREEZE.
- Use only within 28 days upon mixing.
Administration Guide
- Injection route: Abdomen, thigh or back of arms through subcutaneous injection
- Timing: Administer your cagrilintide 1-3 days after your tirzepatide dose at any time of day; consistency is key.
Injection Technique
- Clean vial rubber stopper & injection site with alcohol swabs
- Insert needle at a 45–90° angle into subcutaneous tissue
- Inject slowly & rotate sites (abdomen, thigh, etc.)
Storage Instructions
Discard within 28–30 days after reconstitution, but discard earlier if it appears cloudy, discolored, or contains particles. Always follow proper sterile technique when handling the vial to ensure safety and maintain the integrity of the medication.

While reconstituted peptides can last up to 12 weeks in the fridge, it is recommended to ONLY use within 28 days for maximum potency. It can be used up to 35 days only with caution, ensuring proper refrigeration and minimal exposure to temperature fluctuations.